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Oral-Turinabol

(4-chlorodehydromethyltestosterone)

Manufacturer: Underground Labs only
Effective Dose (Men): 10-40mgs/day
Effective Dose (Women): 5-15mgs/day
Active life: 16 hours
Detection Time: 6 weeks
Anabolic/ Androgenic ratio: >100: >0

Oral Turinabol was first developed by scientists in East Germany for their Olympic and national-level athletes to use. This, plus the eventual removal of it from the market caused OT to become a very “sexy” drug for athletes to try to obtain. The East Germans studied this drug pretty extensively for many years and some of the success of this now defunct country was attributed to this drug. It made its first appearance to athletes in East Germany as little blue “Vitamins” their coaches gave to them. This drug has been discontinued by all of the major pharmaceutical houses, and is only found through certain underground labs. Although some UnderGround Labs have access to this item and it appears on their price-lists, it’s still rare enough.

The easiest way to explain this drug is that it is a derivative of Dianabol, but still quite different. Remember, Equipoise is esterified Dianabol, and really has nothing in common with it in terms of real-world¬effects. The first similarity between Oral Turinabol and Dianabol is that they have been 17-alpha-alkylated (a carbon atom was added at the 17th position) to survive the first pass through the liver. This, of course, increases hepatoxicity (liver toxicity). OT has a much lower level of androgenic activity compared to dianabol, but has a better balance/ratio of anabolic and androgenic effects. It has a rating of a 0 (according to the Vida reference) for androgenic properties and a 53 for anabolic properties based on a score of 100 each for testosterone. This promotes more of a “hard” look, or what competition bodybuilders often call “quality” muscle. You do not get the same “puffy’ look as you would on d bol, and many people have thus compared the results they’ve gotten from OT to Anavar. Actually, though, this stuff is simply dianabol with a 4-chloro alteration, the same alteration found in Clostebol.

Due to this 4-chloro substitution in the A-Ring of its Steran Nucleus, this drug cannot be aromatized (3). This is, as you know, quite beneficial and is one of the reasons Oral Turinabol has been called a “gentle d-bol.” You will probably not get any typical estrogenic side effects like water retention, acne, gyno, etc. with any dose of this drug. A couple of studies were examining male athletes over a period of six weeks who were given 10 mg OT/day and did not show any indication of health-threatening effects. It has been recommended that men should take between 20-40mg every¬day and women a 5mg everyday. It may perhaps be used in low(er) doses if it is simply being used for its ability to reduce SHBG’s binding (1) to other steroids. In this respect, it may have synergy with other drugs since it has the ability to reduce SHBG and free up more testosterone for use in the body.

The only negative thing about this drug is that in high doses (10+mg) virilization has been seen in women (14) and there has been at least one case of testicular tumors, and one case of a guy who suffered adverse effects from 5 years of high-dose use of OT (2)(4). It should be noted that the former East Germans did many experiments with this drug in high doses though, and found it to be a very suitable compound for their athletes. Many of the women suffered virilization at higher dosages, though. During the 68-72 Olympic cycles, the East German Sports OT program made its biggest impact. It was around this time that the East German weightlifters were taking over 10g/year of OT, and their leading male sprinter was taking under 730mgs/year of OT (14). I think this tells me that for real weight gains and huge gains in the weight room, you’re going to need bank-breaking doses of this stuff. On the bright side, if you are an athlete looking to get faster, a little bit of OT will get you there pretty easily and with minimal (if any) side effects. I think that its inability to cause negative side effects and its ability to produce a favorable increase in lean body mass, thus, causing a favorable increase in strength/speed makes this substance popular. An athlete’s strength: bodyweight ratio is what turned the East German coaches and scientists on. It must be noted that, at the time, this stuff was mostly undetectable and that was certainly a sought after trait by the East Germans who were looking to circumvent the drug testing procedures of the IOC. Now, of course, OT is detectable once it’s administered to man because three major metabolites are formed: 6 beta-hydroxy-turinabol, 6 betas, 12-dihydroxy-turinabol, and 6 beta, 16-dihydroxy-turinabol (5)(8)(9). All of those metabolites are now detectable by drug screeners. In much smaller quantities at least another three metabolites are excreted, one of which could be identified as 17 epi-turinabol (5), and is easily detected by modern drug tests. No measurable amounts of OT itself are detected in any of the urine samples investigated in sport’s doping procedures, but the presence of the metabolites is enough to warrant a positive result and a failed test. Keeping all of this in mind, it is still important to note that the rate of metabolism and urinary excretion or Oral-Turinabol is reasonably fast (5), even though it is technically eliminated biphastically (in two stages) by the body with a terminal 16hr half life (1). OT is notorious for increasing the time it will take for your blood to clot because it has spontaneous fibrinolytic properties. “Fibrinolytic effects” means that the destruction of fibrin (an insoluble fibrous protein produced in the liver from the soluble protein) is happening in your body. Fibrinogen is important during the blood clotting process. It is a soluble protein in the blood that is converted to insoluble fibrin by the action of the enzyme thrombin in response to tissue damage. (6)(7) Thus, you will bleed for longer than usual when on this stuff.
OT is a potent lean tissue builder, and good for cutting. But that’s mostly of interest for bodybuilders. Now, with regards to athletics, what kind of results can we expect? The old East German literature reported that their world class strength athletes were making some pretty remarkable improvements on OT over a 4 year Olympic training period: Male Shot-putters were adding 2.5-4m to their shot throws, 10-12m on their Discus throw, and 6-10m to their Hammer throws. Female athletes gained even more. Let’s take a look at a chart representing the improvements made by one particular female strength athlete (she held the World Record for the shot put, at the time of her beginning OT administration) over the period of July 18 1968 through October 13 1972. During this time, she was taking OT and she improved her throw from under 18m to over 20m (yes, this is a 2m+ improvement to a world record holding throw in one Olympic Cycle). She was taking roughly 5-15mgs/day of OT in the beginning, but worked up to 35mgs/day before she was done with her Olympic cycle. Her throws even while “off” OT even improved a bit, leading to speculation that there are a lot of permanent gains to be had with OT. Anyway, here are the charts representing her intake of OT, as well as her improvements over her 4 Year over her 4 year Olympic training regimen.

Did all of this work for anyone else? Virtually everyone who was involved with the East German Olympic Training program was on some kind of steroids, but OT was by far the most popular. They had access to some pretty weird stuff, too, like intranasal testosterone, etc…
From the literature on this compound it is obvious that women much more positive effects from OT did than men (this is generally true of all steroids). Women also showed more side effects and generally found the side effects to be more severe and unbearable than their male counterparts. Unfortunately, they sometimes tended to use higher dosages than the men did; often up to 2 times as high. Let’s take a look at their typical yearly doses:

Annual dosage of OT in mgs followed by events:

  • 3680 Shot-put
  • 3190 Discus
  • 2900 Shot-put
  • 2615 Shot-put
  • 2590 Shot-put
  • 1670 Sprint
  • 1560 Hurdles
  • 1480 Hurdles
  • 1474 Sprint
  • 1460 Sprint
  • 1450 Shot-put
  • 1405 Sprint
  • 1380 Heptathlon
  • 1375 Sprint
  • 1340 Heptathlon
  • 1255 Discus
  • 1230 Heptathlon
  • 1230 Hurdles
  • 1185 Javelin
  1. Additional injections of testosterone esters have not been considered here.
  2. At least 12 of the drug-receiving competitors listed in this table set world records. In keeping with Journal policy regarding confidentiality of patients and subjects, the names of subjects have been omitted.

Is the recent reappearance of Oral-Turinabol on the black market going to change athletics or bodybuilding dramatically? No. A combination of price ($1/10mgs average) and availability may cause this stuff to remain an understated tool at our disposal. It is, however, a viable tool in a lean mass cycle, cutting cycle, or any athlete’s drug intake routine.

References:
1. [The pharmacokinetics of Oral-Turinabol in humans] Pharmazie. 1991 Sep; 46(9):650-4. German.
2. Department of Urology, Universitaetsklinikum “Carl Gustav Carus,” Technical University of Dresden,Dresden, Germany
3. Influence of 1-double bond and 11 beta-hydroxy groups on stereospecific microbial reductions of 4-en-3-oxo-steroids. J Steroid Biochem. 1986 Oct; 25(4):561-6.
4. Intratesticular leiomyosarcoma in a young man after high dose doping with Oral¬Turinabol: a case report. Cancer. 1999 Oct 15; 86(8):1571-5.
5. GC and capillary column GC/MS determination of synthetic anabolic steroids. II. 4- chloro-methandienone (oral turinabol) and its metabolites. J Chromatogr Sci. 1983 Sep; 21(9):405-10.
6. [Activation of the fibrinolytic system with dehydrochlormethyltestosterone] Folia Haematol Int Mag Klin Morphol Blutforsch. 1984; 111(4):556-62. German.
7. [Modification of hypofibrinolytic states by dehydrochlormethyltestosterone] Folia Haematol Int Mag Klin Morphol Blutforsch. 1984; 111(4):563-6. German.
8. [Application of microbial enzymes in studies of steroid metabolism ( author's transl)] Acta Microbiol Acad Sci Hung. 1975;22(4):397-402. Review. German.
9. [Application of microbial enzymes in studies of steroid metabolism ( author's transl)]
10. [ON THE PHARMACOLOGY OF "ORAL TURINABOL".] Dtsch Gesundheitsw. 1965 Apr 15; 20:690-1. German. No abstract available.
11. Berendonk B. Doping. Von der Forschung zum Betrug. Reinbek bei Hamburg: Rowohlt Taschenbuchverlag. 1992:448pp
12. [4-CHLORO-DELTA-1-METHYLTESTOSTERONE (ORAL TURINABOL), A NEW EFFECTIVE ORAL ANABOLIC STEROID.] Dtsch Gesundheitsw. 1965 Apr 15; 20:670-4. German. No abstract available.
13. Bauersfeld K-H. Olek J. Meibner H. Hannemann D. Spenke J. Analyse des Einsatzes u. M. in den leichtathletischen Wurf/Stob-disziplinen und Versuch trainingsmethodischer Abteilungen und Verallgemeinerungen. Science Center of the DVfl 1973:41pp.
14. Clinical Chemistry 43:7. 1262-1279 (1997)

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