muscle building blog, workout tips, anabolic steroids use, nutrition and more header image 1


(Testosteone plus testosterone with Propionate, Phenylpropinoate, Isocaproate, and Caproate esters)
(Testosterone + 4 esters)

Manufacturer: Jelfa
Effective dose: 250-1,000mgs/week Active Life: 10 days
Detection Time: 3 months
Anabolic/Androgenic Ratio: 100:100

1 milliliter of Omnadren 250 contains:

  • 30mg testosterone propionate
  • 60mg testosterone phenylpropionate 60mg testosterone isocaproate
  • 100mg testosterone caproate

Omnadren 250 is a combination of the 4 separate test esters listed above. Older versions of the drug, list the final two esters as ‘isohexanoate’ and ‘hexanoate.’ However, it should be noted that hexanoate is simply another word for caproate, so the drug’s esters have not actually been modified. Most commonly, people will correlate Omnadren 250 with its cousin Sustanon 250, since they are both a blend of 4 test esters. The only difference between the two lies in the last and most concentrated-ester. Whilst Omnadren contains the caproate ester, Sustanon contains the decanoate ester in the same concentration. Really, except for price, there’s no difference between them, and price-wise, you’re going to be paying half as much for Omnadren as you would for Sustanon.

It is also not uncommon to hear people refer to Omnadren as a superior version of testosterone since it boasts 4 esters instead of 1 (or none). This should be taken with a grain of salt. All testosterones produce very similar effects, while the ester simply delays the release of the compound into the body, which has two immediate consequences. The first being less important: injection frequency. This has recently become a hotly debated issue. On one side, there are those who advocate injections only once or twice a week. Their arguments are supported frequently with cycle results that have yielded ‘good gains.’ On the other side, perhaps the more scientific side, are those who advocate injections at least every-other-day (EOD) or everyday (ED). One only has to glance at the ester constitution in Omnadren to understand why this is so. Such small concentrations of the shorter esters (propionate and phenylpropionate) are rendered practically useless when Omnadren is injected once or twice a week. Furthermore, when injecting only a few times a week the “peaks and valleys” of concentration in the blood are not desirable. We want our blood concentration of the drugs to be as high as they can be -relative to dose- as long as they can be. Obviously, this is not the case when fast acting esters are introduced and subsequently dissipated before another injection is given.

The longest ester in Omnadren (caproate) is slightly faster acting than the longest ester in Sustanon (decanoate), and users will notice an increase in their testosterone levels sooner with Omnadren than with Sustanon. This has a few consequences that we shall examine now. First of all, since testosterone aromatizes (converts) to estrogen, a buildup of this female hormone will occur more rapidly. Estrogen increase follows the inevitability of increased water retention. This is significant for 3 reasons. First, the user’s strength will increase. Secondly, the user’s size will increase, and finally, definition in the muscles will begin to dissipate. As a result, Omnadren is typically used more for bulking than cutting. The extent of these effects are highly dictated by the user’s diet and training habits; although, it is also easily controlled with the proper use of anti-estrogen drugs such as Nolvadex, Arimidex, Proviron, and a myriad of others.
As I previously stated, testosterone is a highly anabolic and androgenic hormone, and it has an anabolic (muscle building) rating of 100, making it a good drug to use if one is in pursuit of more size and strength. And if you aren’t in pursuit of more size and strength, then why would you be reading this, right? Well, let’s get on with it and look at exactly what makes testosterone a good mass builder. First, testosterone promotes nitrogen retention in the muscle (6). The more nitrogen the muscle holds the more protein the muscle stores. Testosterone can also increase the levels of the highly anabolic hormone, IGF-1, in muscle tissue (7)(9). Even the aromatized part of testosterone that turns into estrogen may increase levels of IGF, and it may also increase sensitivity to it. Testosterone’s actions come mostly from its binding to the androgen receptor to promote A.R dependant mechanisms for both muscle gain and fat loss (5). Thankfully, it also significantly increases the concentrations of the A. R in cells critical for muscle repair and growth and A.R in muscle (8). Testosterone induces changes in shape; size and also can change the appearance and the number of muscle fibers (7). Androgens like the testosterone(s) found in Omnadren can protect your hard earned muscle from the catabolic hormones (8), whether those hormones occur from exercise or other stress.
There are strong androgenic side effects, which are pronounced with Omnadren (as with all testosterones). Oily skin, acne, increased body/facial hair, and, depending on the individual, an increase in aggressiveness can occur. Omnadren can also be hard on the hairline. This is partly due to the conversion of the testosterone into dihydrotestosterone (DHT). Test is converted to DHT via the 5-alpha reductase enzyme. DHT is more potent than test at the androgen receptor (the double bond is removed from the carbon4-carbon5 bond and replaced with a hydrogen atom on each) and is responsible for some growth. It can also cause some negative side effects as well. Because of this bond, Testosterone is actually much more anabolic. For example: DHT formation in the scalp is suspected of causing/expediting male pattern baldness. To possibly combat this, one can use finasteride (Proscar®). This drug will inhibit the conversion of testosterone to DHT, but many users will report that since DHT is more potent at the androgen receptor than test, gains in muscle mass, as well as strength, will diminish. On the other hand, a lack of DHT caused by blocking 5-AR can sometimes cause gynecomastia (4)(5).

Typically, cycles that contain Omnadren 250 will be around 12-16 weeks. The idea is that it will take at least 2 weeks for the compound to become fully ‘active’ in the body, and most users will report an additional 1-3 weeks until the effects of Omnadren are truly felt. As a result, gains from Omnadren are not typically noticed for about 1 month after the first injection. What most people mean by this is that, although the actual drug is already active, gains aren’t realized immediately. The majority of users will supplement a fast acting oral drug such as Dianabol or Anadrol in the first 4 weeks of a cycle, which is thought of as a ‘kickstart’ until the effects of the Omnadren are fully felt. As mentioned above, a typical weekly dose of Omnadren can range from 500mg-1000mg per week. Those who are new to steroids and cycling should generally start with a minimal dose to better judge how their own bodies will react to the synthetic testosterone. I suggest that beginners stick with 2 amps per week if they’re inclined to use this preparation.

Omnadren has always been manufactured by Polfa©, who have changed their name to Jelfa©. The company is based in Poland, and as one might obviously conclude, the availability and price of Omnadren 250 is different in many places. Often, fake Sustanon in the 80’s would actually turn out to be Omnadren, which was much less highly prized (nonsensically).

1. Hypothalamic sites of action for testosterone, dihydrotestosterone, and estrogen in the regulation of luteinizing hormone secretion in male sheep. Endocrinology. 1997 Sep; 138(9):3686-94.
2. Inhibition of LH Secretion by Localized Administration of Estrogen, but not Dihydrotestosterone, Is Enhanced in the Ventromedial Hypothalamus during Feed Restriction in the Young Wether. Biol Reprod. 2005 Jun 22; [Epub ahead of print]
3. Crystalline dihydrotestosterone implants in the lateral septum of male rats. A positive effect on LH and FSH. Endocr Res. 2001 Feb-May; 27(1-2):35-40.
4. Significant role of 5 alpha-reductase on feedback effects of androgen in rat anterior pituitary cells demonstrated with a nonsteroidal 5 alpha-reductase inhibitor ON0-3805. J Androl. 1994 Nov-Dec; 15(6):521-7.
5. Case report: fmasteride-induced gynecomastia in a 62-year-old man. Am J Med Sci. 1995 Jun; 309(6):322-5.
6. J Clin Endocrinol Metab. 1997 Feb; 82(2):407-13.
7. Am J Physiol Endocrinol Metab. 2002 Mar; 282(3):E601-7.
8. Curr Opin Clin Nutr Metab Care. 2004 May; 7(3):271-7.
9. Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3. Maturitas. 2005 Jul 16; 51(3):286-93.